Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
A CASE OF RAPID RELAPSING DIFFUSE PULMONARY LESION IN HODGKIN'S DISEASE
Kouji ICHIHASHIMasahisa INABATsutomu HIRANOYu SHIRATORIHirotsugu IDETestuzo SUGISAKIYoshihiko SUGIYAMA
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1988 Volume 48 Issue 2 Pages 277-280

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Abstract
Pulmonary involvement is more common in Hodgkin's disease and is always accompanied by mediastinal and hilar lymphadenopathy. We describe a rare case of rapid relapsing diffuse pulmonary lesion in Hodgkin's disease. Case: In 1977, a 72-year-old man progressively lost weight (5 kg) and became aware of fever and left axillary lymph adenopathy. Axillary lymph node disclosed Hodgkin's disease of the mixed cellular type. He received COPP (Cyclophosphamide, Vincristine, Procarbazine and Prednisolone) treatment, which introduced complete remission of Hodgkin's disease. After the one year and two months, he became aware of high fever and dyspnoe. Radiograph of the chest disclosed diffuse shadow throughout both lungs. The patient died in late 1978 from Hodgkin's lung. Histopathology revealed diffuse infiltration of lymphoid cells and Hodgkin's cells in pulmonary intraparenchymal tissue of both whole lung tissue.
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