All issues
Successor
Volume 48 (1988)
- Issue 6 Pages 665-
- Issue 5 Pages 553-
- Issue 4 Pages 437-
- Issue 3 Pages 301-
- Issue 2 Pages 153-
- Issue 1 Pages 13-
Volume 48, Issue 2
Displaying 1-15 of 15 articles from this issue
- |<
- <
- 1
- >
- >|
-
[in Japanese]1988 Volume 48 Issue 2 Pages 153-158
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (613K) -
Takao BABA, Hideyuki MUKAI, Youichi KOBAYASHI, Hirokazu NIITANI1988 Volume 48 Issue 2 Pages 163-174
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe clinical significance of sinus node recovery time (SRT) after pharmacologic autonomic blockade (PAB) was evaluated in 49 sick sinus syndrome (SSS) patients. Patients with SSS were classified into three groups according to the SRT before PAB and the change ratio of corrected sinus node recovery time (CSRT) before and after PAB as follows : Group A had an SRT before PAB of less than 5000 msec and a CSRT change ratio of less than 200 % ; Group B had an SRT before PAB of less than 5000 msec and a CSRT change ratio of more than 200 % ; and Group C had an SRT before PAB of more than 5000 msec. There is no difference of SRT between Groups A and B before PAB, while the SRT in Group B lengthened significantly (P<0.01) and was similar to Group C after PAB. Clinical findings including central nervous system (CNS) symptoms, CTR and pacemaker implantation in Groups B and C were significantly severer than those in Group A. The max R-R interval was more prolonged in Groups B and C than in Group A. Furthermore, a higher sympathetic nervous tone was noted in Group B than in Group A by the % chronotropy. In conclusion, some patients with an SRT of less than 5000 msec before PAB belonged to the severe Group ; therefore, it is useful to consider an SRT after PAB and a change ratio of CSRT for determining the clinically severe Group.View full abstractDownload PDF (1367K) -
Makoto YAIDA, Yumiko UMEZAWA, Noburu KONNO, Takashi KATAGIRI1988 Volume 48 Issue 2 Pages 175-183
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe studied alterations in diabetic heart muscle by the biochemical analysis of the sarcoplasmic reticulum (SR) and the structural proteins. Experimental diabetes mellitus was produced in rats by single intravenous injection of streptozotocin for 1 to 16 weeks (DM group) and insulin was injected subcutaneously for 2 to 4 weeks for rats selected as DM+I group. Fasting blood glucose was markedly elevated to greater than 400 mg/dl in DM group.In DM + I group, these levels were controlled 113.5 and 131.0 mg/dl on the average in rats of 2 and 4 weeks, respectively. Body and heart weights were significantly lesser at the time of sacrifice in DM group than in normal controls (C group) and DM+I group, but heart/body weight ratio was higher in DM group from 4 weeks. Both of Mgr++-and Cap++-ATPase activities of SR depressed significantly to 35 and 42 % of C group at 1 week in DM group, respectively, reduced further until 2 to 16 weeks. Cap-ATPase activity of structural proteins decreased gradually in DM group to 18 to 36 % of C group from 4 to 16 weeks. In SDS gel electrophoresis, the pattern of structural proteins in DM group was similar to that in C group, but in SR of DM group about 100 K dalton protein increased significantly from 4 weeks, suggesting an increase in the major ATPase protein. In DM+I group all of these alterations were inhibited significantly. These results indicate that SR is damaged in the early stage of diabetes, and induce relaxation disturbance in the diabetic heart.View full abstractDownload PDF (2304K) -
Hidefumi HIROSE1988 Volume 48 Issue 2 Pages 185-204
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESS24 femoral heads of patients with intracapsular fracture of the femoral neck were examined. These materials were classified 3 fracture types according to Minamisawa's classification, i.e., typical type, mixed type and crescent type. These specimens were examined by a soft x-ray, contact-microradiography, histological and osteo-morphometrical methods. Consequently, in the cases of typical type, it is was suggested that there was a possibility of bone remodeling to fracture healing when reserched in histological examination and histomorphmetry, because of an opened inferior retinacular artery, one of capital nutrient artries, was observed. On the other hand, in the cases of mixed and crescent type, an opened nutrient arteries were not observed in the capitatum. In addition, fracture healing in these 2 types was considered to be very little possibility, because of osteoporotic findings of cancellous bone and less amount of bone marrow in these capitatum.View full abstractDownload PDF (29271K) -
Kazuhiko UMETSU, Mamoru MOCHIZUKI, Toshikuni YANAGISHITA, Takashi KATA ...1988 Volume 48 Issue 2 Pages 205-213
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe studied changes in the fatty acid composition of membrane phospholipids in sarcoplasmic reticulum (SR) and mitochondria (Mt) in the acute ischemic myocardium in the dog with the occurrence of severe ventricular arrhythmia such as ventricular tachycardia. The arrhythmia group (A group) was defined grade 3 or higher in Lown's classification and the others regarded non-arrhythmia group (NA group) . Total phospholipid contents of SR and Mt decreased significantly in the ischemic myocardium for 1 and 3 hrs in both of A and NA groups, and a significant decrease in arachidonic acid was noted in SR of A group. By treating SR from the normal heart muscle with exogenous phospholipases (PLase) A2and C, marked reduction in total phospholipid contents were observed in treatment with PLase C. Treatment with PLase A2brought similar reduction in arachidonic acid in A group. These results suggest that membrane degradation occurs with the activation of PLase C in the acute ischemic myocardium and further advances with the activation of PLase A2, mainly the release of arachidonic acid, resulting in the occurrence of severe ventricular arrhythmias in the acute ischemic myocardium.View full abstractDownload PDF (1023K) -
Sanemasa TOGO, Tetsuya NAKAYAMA, Hidenosuke ARAKI, Kazuyuki SUZUKI1988 Volume 48 Issue 2 Pages 215-232
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTo study the relationship between the development of pelvis in children during adolescent and the height of their parents, 95 boys and 104 girls of 6-year-old were selected. Longitudinal study for external measurement of pelvis and height of the children for 12 years was undertaken. Height of their parents were examined by questionnnaire. The results were as follows: 1) When children were devided into three groups, according to their height, i. e., large (L), medium (M), and small (S), both height and pelvis in each group grew in the same proportion during the period studied. Height and body weight of the children at birth are correlated with the height of their parents. 2) When the children were devided into L and S groups according to their height at birth, height of parents in L was greater than that in S, and height and the size of pelvis in girls of L group are greater than those of S group up to the age of 12-14. 3) When the parents were devided into two groups (L and S) according to their height, positive correlation was observed between the development of hight and pelvis of girls and the height of their parents. Height and the size of pelvis of the children born from L parents were greater than those from S parents. 4) Multiple regression analysis also demonstrated the positive correlation between height of the parents and the growth of height of their girls till the age of 17, and development of pelvis till the age of 14. These results suggest that the development of pelvis in girls is closely related hereditarily to the physical factor of their parents.View full abstractDownload PDF (1868K) -
—The investigation of amylase isozyme and ACCR—Toshihiro SAKURAI, Yasushi TAKAGI1988 Volume 48 Issue 2 Pages 233-238
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSSerial changes of amylase and amylase isoenzyme in body fluid before and after laparotomy were investigated in 50 patients. Serum amylase activity was diminished 1 to 3 hr after operation and was elevated at 12 hr. Total activity reached a maximum at 24 hr postoperative (24 hr preoperative baseline is 2.78±0.53 (X±SE) ) . Thereafter, serum amylase activity decreased gradually to baseline after 3 to 5 days postoperative. Meanwhile pancreatic P-amylase did not change significantly from preoperative levels. In contrast, fluctuation of S-amylase from the salivary glands and intestines was similar to that of the total activity, suggesting that transient hyperamylasemia after laparotomy is attributable to S-amylase activity. There was no direct relation between hyperamylasemia and operative time or target disease. This suggests that the elevation of serum amylase activity is mediated by a nonspecific mechanism. The 24 hr postoperative amylase-creatinine clearance ratio (ACCR) was 4.43±1.55 (%) . This was significantly (p<0.05) higher than the preoperative level of 3.73±1.0 (%) (X±SD) . In particular, the ACCR of S-amylase compared with that of P-amylase was not elevated. showing that this could be a factors in postoperative hyperamylasemia.View full abstractDownload PDF (2021K) -
Mitsuyoshi MATSUMURA1988 Volume 48 Issue 2 Pages 239-247
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSRelationship between mean platelet volume (MPV) and platelet count (Pit) vary inversely and non-linearly under normal bone marrow function, and the MPV-Plt relationship differs markedly according to whether the condition of decreased thrombopoiesis in myelosuppression. The purposes of this study were 1) to obtain a nomogram of MPV-Plt in normal subjects in pediatric age group, 2) to evaluate the marrow function in pediatric patients with myelosuppression following myelosuppressive regimen for malignant solid tumor, and 3) to develope the appropriate clinical assessment for damaged marrow. The nomogram obtained in 135 normal subjects was classified into 5 areas : Area A-B defined as Plt over 100, 000 per cubic milliliter MPV within its normal range, compatible for normal marrow; Area C, as Plt over 100, 000 per cubic milliliter despite MPV lower than nomogram range, suggesting mild suppression; Area D, as marked decline in both MPV and Plt, suggesting obvious myelosuppression at its lowest; and Area E, as MPV over 9.5 fl and Plt less than 100, 000 per cubic milliliter, compatible for recovery from myelosuppression. This assessment for suppressed marrow function was useful for making clinical decision for supportive therapy and/or modification of on-going treatment protocol.View full abstractDownload PDF (903K) -
Junichi SHIOTA, Toshiyuki MAKI, Yoshio SUZUKI, Yutaka SATOH, Osamu ISO ...1988 Volume 48 Issue 2 Pages 249-255
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe purpose of the present study was to evaluate the regeneration process in the experimental ischemic myopathy and to elucidate the relationship between the severity of necrotic lesion and vascular distribution. The experiment was conducted on 15 adult cats. Ischemic muscle was prepared by ligation inferior region of abdominal aorta, the right common iliac artery and the right femoral artery for 7 hours simultaneously. The animals were sacrificed on 7th, 10th and 14th days after the surgery, and the lesion of crural muscle was histochemically examined. The result of the experiment were as follows: (1) In the distribution of necrosis of crural muscle, outer surface of the muscle and around the main artery in the muscles were tend to save from necrosis. The necrosis of anterior tibial muscle (hereinafter referred as“Ta”) was distributed segmentally on both proximal and distal sites, while proximal site of medial gastrocnemius muscle (Gm) and soleus muscle (Soleus) were affected by the ischemia. (2) Severity of ischemic changes in each crural muscle group was observed as Ta≥Gm≥Soleus. (3) Distribution of regenerated fibers and its maturation process: After 7 days of ischemia, amorphous myoblast having prominent muscle within the large nucleus, appeared at the boundary areas between necrotic lesion and normal tissues. After 10 days of ischemia, most of the ischemic lesion was occupied by small round muscle fibers having 1/2-1/3 of the diameter compared with that of normal fiber. The more matured regenerated fibers were seen outside, and the myoblast were recognized in the center of necrotic lesion. After 14 days of ischemia, both myoblast and small round muscle fibers were almost disappeared, and the matured regenerated fibers were seen scattered among the normal fissures. They did not differ very much from normal fibers except the central nucleus and disarrangement of intermyofibrillar network. Conclusion: Regeneration process in experimental ischemic myopathy did not show uniform maturation. It's depend on the severity of ischemic damages of the muscles and might be related deeply with blood supply to the ischemic muscles.View full abstractDownload PDF (5736K) -
Hajime SAKAGAWA1988 Volume 48 Issue 2 Pages 257-268
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe patients with spondylolysis or spondylolisthesis in the lumbar region, who had been cared not less than 10 years since they were first diagnosed as such, were studied in order to elucidate the natural history of these diseases. The subjects were 55 in all. The age of the patients ranged from 4 to 75 years old (40.5±15.9 years old on the average) at the time of first diagnosis. The period of time which had paseed since their first diagnosis ranged from 10 to 16 years (11.6±1.5 years on the average) . As a result, JOA score for clinical symptoms was improved from the average score of 24.7±2.3 at the time of first diagnosis to the average score of 27.1±2.8 at the time of this study, though no case was improved in the roentogenography. Only 4 cases (their score at the time of this study were 14, 17, 24, and 25, respectively) were found worse. The improvement in the score for the activitied of daily living contributed to the improving tendency at the time of this study. In conclusion, the conventional conservative therapy should be taken to treat the patients with spondylolysis, and preventive operation is not considered necessary even for the treatment of the patients with complication of spondylolysis and spondylolisthesis.View full abstractDownload PDF (2965K) -
Mitsutaka KADOKURA, Toshihiro TAKABA, Noboru TANIO, Mototoshi YAMASHIR ...1988 Volume 48 Issue 2 Pages 269-272
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA pediatric tracheostomy tube (portex cannula: ID. 4.5mm, OD. 6.2mm) is utilized for postoperative or terminal stage cancer patients. In these patients, intratracheal secretions are very mucous and purulent, so it is difficult to remove these secretions through nasal or orally inserted suction tubes. If endotracheal intubation is contra indicated and there is need for suction of mucopurulent secretion, it is suggested that this be done by inserting a pediatric tracheostomy tube by coniotomy (cricothyroid tracheostomy) . This should permit ready aspiration of pus; the amount depending on the technique. This procedure is considered very useful for patients unable to excrete secretion.View full abstractDownload PDF (2202K) -
Hideaki KAMATA, Yoshitomo KIKUCHI, Kenichi HIGUCHI, Keiichiro YONEYAMA ...1988 Volume 48 Issue 2 Pages 273-276
Published: April 28, 1988
Released on J-STAGE: November 19, 2010
JOURNAL FREE ACCESSThe purpose of this report is to demonstrate porcelain gallbladder in sixty-seven years old lady and also analized the composition of gallstones and the structure of gallbladder wall. Calcified shadow with oval shape was observed in abdominal plane X ray film. Porcelain gallbladder with common bile duct stone was diagnosed and operation was perfomed. The gallbladder wall was felt as stonelike hard. The gallbladder contained shallow yellowish mixed cholesterol stone and adhered with liver tightly by inflammation change. The color of common bile duct stone was black. The same analysis pattern was obtained from gallbladder and common bile duct stones by infrared absorption spectrophotometory. It contained cholesterol over 95% and calcified components was mainly calcium phosphate and calcium bilirubinate. Gallbaldder wall could not be analyzed because of impure substances. Porcelain gallbladder of our case was caused by chronic inflammatory changes and stasis of bile subsequence to longstanding cystic duct obstruction. We consider that common bile duct stone had existed for long period without any symptom, therefore cystic and common bile duct stone had similar composition, which led to the obstruction of cystic duct. We recommend the early operation of porcelain gallbladder because of high risk evidence of gallbladder carcinoma in the clinical course.View full abstractDownload PDF (3626K) -
Kouji ICHIHASHI, Masahisa INABA, Tsutomu HIRANO, Yu SHIRATORI, Hirotsu ...1988 Volume 48 Issue 2 Pages 277-280
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSPulmonary involvement is more common in Hodgkin's disease and is always accompanied by mediastinal and hilar lymphadenopathy. We describe a rare case of rapid relapsing diffuse pulmonary lesion in Hodgkin's disease. Case: In 1977, a 72-year-old man progressively lost weight (5 kg) and became aware of fever and left axillary lymph adenopathy. Axillary lymph node disclosed Hodgkin's disease of the mixed cellular type. He received COPP (Cyclophosphamide, Vincristine, Procarbazine and Prednisolone) treatment, which introduced complete remission of Hodgkin's disease. After the one year and two months, he became aware of high fever and dyspnoe. Radiograph of the chest disclosed diffuse shadow throughout both lungs. The patient died in late 1978 from Hodgkin's lung. Histopathology revealed diffuse infiltration of lymphoid cells and Hodgkin's cells in pulmonary intraparenchymal tissue of both whole lung tissue.View full abstractDownload PDF (3610K) -
Atsubumi MURAKAMI, Kazuo KOIZUMI, YOKO KOIZUMI1988 Volume 48 Issue 2 Pages 281-285
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSGenerally, lymphangioma is divided into three classes, i.e., simple, cavernous and cystic. Among these types, cystic lymphangioma originating from retroperitoneal lymphatic vessels is rare, and especially those containing chylous fluid are very uncommon. Cystic lymphangioma, usually found in children aged about ten years, and particularly in males, may follow a proliferative and invasive course. Recently, an 8-year-old boy was admitted to our hospital with upper abdominal pain one week after blunt abdominal trauma. Abdominal examination suggested acute abdomen and surgery revealed retroperitoneal cystic lymphangioma beside the second portion of duodenum containing chylous fluid with no other abnormal findings. In this case, the cyst disappeared after internal drainage. It seems that the surgical goal should be complete excision whenever possible, since recurrence sometimes follows sucessful resection.View full abstractDownload PDF (3667K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1988 Volume 48 Issue 2 Pages 287-299
Published: April 28, 1988
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (1648K)
- |<
- <
- 1
- >
- >|