Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
A STUDY OF INHERITANCE OF SCHIZOPHRENIA
Kyoko OHIWAKenji TAKEMURA
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1989 Volume 49 Issue 2 Pages 187-193

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Abstract
Symptoms forming the core of schizophrenia were observed to view factors underlying heredity. The study was performed according to the conventional method of analyzing every pedigree obtained, in which each patient appeared as a propositus. We focused particularly on the occurrence of the same type of schizophrenia in relatives up to the third degree from the pedigree, and clinically determined the relation of the disease with personalities of parents, through whom the relative was connected to the pedigree. The core symptoms categorized as type 3 schizophrenia were strongly suspected to have dominant heredity. It seemed reasonable that monogenic locus plays a main role in the occurrence of schizophrenia, in which other supporting genes, penetrance, expressivity and environmental influences are also involved. Through this study, we felt that the most important matter to be revealed was that a way of returning to society is opened to the patient through treatment of schizophrenia, including rehabilitation and drug medication.
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