Abstract
Cases are described in which sympathetic ophthalmia occurred due to multi-factor cumulative effects such as those caused by injection of silicone oil, multiple vitrectomy, and retinal detachment operation. Despite preservative therapy for the subsequent three and a half years, uveitis attacks recurred six times, and the damaged eye had to ultimately be extracted. Pathological examination revealed lymphocyte infiltration, and the formation of granuloma of epithelioid cells on the iris and choroidea. The retina was detached, and there was silicone oil below and within the retina. The silicone oil was partially enclosed by macrophages. Cases of sympathetic ophthalmia after vitrectomy or retinal detachment operation may increase further in the future.