A CASE REPORT OF RELATIVELY LONG-TERM SURVIVED ESOPHAGEAL CANCER TREATED BY THE ENDOSCOPIC COMBINATION THERAPIES

Abstract

An 83-year-old woman was admitted to our hospital for operation on a small elevated lesion of the esophagus. Endoscopic examination revealed a small (about 1 cm) abnormal elevated lesion of the esophagus. The lesion was diagnosed by endoscopy as a superficial, elevated type of esophageal cancer. Biopsy showed moderate differentiated squamous cell carcinoma. From endoscopic ultrasonographic findings, the invasive depth of the lesion was diagnosed submucosa, and no lymphnode metastasis was evident. Her advanced age and respiratory disfunction contraindicated radical operation, and we elected combined modality therapies, composed mainly of endoscopic therapy. We performed endoscopic laser therapy, radiation therapy, PANa oil BLM peroral contact therapy, and OK 432 local injection therapy, but complete histological response was not achieved. Finally we performed endoscopic palliative intubation to improve her disphagia. She died because of excess hematoemesis. Of her 2 years and 2 months duration clinical course, house medical care was 17 months. She achieved good performance status during her clinical course.