Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 49, Issue 5
Displaying 1-15 of 15 articles from this issue
  • [in Japanese]
    1989 Volume 49 Issue 5 Pages 415-421
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese]
    1989 Volume 49 Issue 5 Pages 422-429
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Toyoaki KAGAWA
    1989 Volume 49 Issue 5 Pages 430-439
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Intraoperative fluid was investigated in 80 patients more than 65 year old. The fluids used in this investigation were lactated Ringer's solution (LR), LR with 5 % glucose (LR-D), acetated Ringer's solution (AR) and AR with 5 % glucose (AR-D) . Infusion rate was 5 ml/kg/h or 10 ml/kg/h. Blood and urinary samples were drawn from patients four times every hour and were analyzed into glycometabolism electrolytes and acid-base balance and renal function. Urinary output of AR groups was higher than that of LR groups but blood pressure and pulse pressure of AR groups tended to decrease. Blood glucose level of LR-D and AR-D groups increased exceedingly compared to those of LR and AR groups, and with an infusion rate of 10 ml/kg/h, all of LR-D and AR-D groups developed hyperglycemia above 300 mg/dl. A tendency toword acidosis was seen in the LR-D and AR-D groups. Narrowing of pulse pressure and low urinary output were seen in the 5 ml/kg/h group. In conclusion, no advan-tage of AR was found in aged patient. Addition of 5 % glucose to the solution was not adequate for aged patients, because of hyperglycemia. Infusion rate of 10 ml/kg/h was sufficient for total infusion volume, but required careful administration depending on the general con-dition of the patient and the state of operation and anesthesia.
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  • Seiichi KUSUMOTO, Hisashi OKA, Shinzou MIYAYAMA, Nobuhiro KOJIMA, Kais ...
    1989 Volume 49 Issue 5 Pages 440-443
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We studied the invasive depth of 80 cases of resected rectal carcinoma. The results were as follows : Classification of the invasive depth was m : sm (12.5 %), pm (28.8 %), ss : a1 (17.5 %), s : a2 (36.3 %) and si : ai (5 %) . There was a relation between the invasive depth, the size of the tumor, and CEA. Well-differentiated adenocarcinoma appeared most often. The proportion of moderately and poor differentiated adenocarcinoma increased in deep invasion. There was a relation between invasive depth and lymphatic invasion (ly), venous invasion (v), and lymph node metastasis. Survival decreased with depth of invasion. Invasive depth is the most important factor in the prognosis of rectal cancer.
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  • Teruo UETAKE
    1989 Volume 49 Issue 5 Pages 444-453
    Published: October 28, 1989
    Released on J-STAGE: November 19, 2010
    JOURNAL FREE ACCESS
    The myofibrous constitution of three cross-sectional regions (proximal, medial and distal) of the muscle, m. quadriceps femoris, and the hamstrings of the crab-eating macaque were compared to determine if there is myofibrous diversity within a muscle. Two adult female crab-eating macaques were fixed with 10 % formalin. After a slice of muscle was dyed using Sudan Black B for microscopic examination, the type (white, intermediate or red) and area of the muscle fiber were examined. The total number of muscle fibers in a defined re-gion was also determined. The results were summarized as follows : 1) The proportion of white fiber type (40-70 %) was highest of the three in all sectional regions of the m. quadriceps femoris and the hamstrings. However, the proportion of the other two types differed from muscle to muscle, and from subject to subject. 2) In the m. quadriceps femoris, especially in the m. vastus lateralis, m, vastus medialis and m. rectus femoris, the proportion of white fiber was higher in the distal than in the proximal region, and the proportion of red fiber was higher in the proximal than in the distal region. 3) In the hamstrings, especially in the m. biceps femoris and m. semimembranosus proprius, the proportion of white fiber was higher in the proximal than in the distal region, and the proportion of red fiber was higer in the distal than in the proximal region. 4) In semimembranosus accesorius, however, the proportions of the three muscle fiber types were similar to those in the m. quadriceps femoris. 5) The area of each muscle fiber type in hamstring was larger than that in m. quadriceps femoris in the following order : m. semitendinosus> m. biceps femoris> m. semimembranosus accesorius> m. semimembranosus proprius> m. vastus lateralis> m, rectus femoris> m. vastus medialis> m. vastus intermedius. Also, the area of each muscle fiber type was generally larger in the prox-imal than in the distal region. The results suggested myofibrous diversity that provides intra-muscular differentiation of two muscle groups.
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  • —BLOOD COAGULATION AND FIBRINOLYTIC ACTIVITY—
    Kuniko OTSUKA, Takako KASAHARA, Katsuji OGUCHI
    1989 Volume 49 Issue 5 Pages 454-458
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Laennec (LAE) is a placenta preparation which has heretofore been used sub-cutaneously or intramuscularly to treat liver disease. The effects of intravenous preparation of LAE on CC14-induced acute liver injury in Sprague-Dawley rats were investigated through measurement of blood coagulation and fibrinolytic parameters (HPT, PT, PTT and fibrinogen content, and activities of factor XIII, AT III, PLG and α2PI) and some biochemical parameters (GOT, GPT, Hematocrit and liver weight/body weight ratio) . Lengthened PT and PTT values due to 0.5 ml/kg CCl4 p.o. were improved by two treatments with 1.0 ml/kg LAE i.v., the first administered with the CCl4. Increase in liver weight/body weight ratio 24h after administration of 1.0 ml/kg CCl4 p.o. was significantly suppressed by pretreatment with 1.0 ml/kg LAE i.v., daily for 4 days.
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  • Sumiko ARIMA
    1989 Volume 49 Issue 5 Pages 459-470
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The human body has individuality as well as complex form. It is rather difficult to understand the morphological characteristics of body form. Measurement of body form has heretofore used only the Martin method, which depends mainly on measurements of the frame. Comparatively new morphological studies of body characteristics depend on shape, and these methods of measurement and classification are not yet established. In the present study, we attempted to understand morphological characteristics of the body form, and sought a method to express and classify them. We discuss here a method of understanding and expressing body form of young women, and a method of classifying those forms. We measured the body form by the silhouette method, the sliding gauge method, and the laser method, and used factor analysis to analyze these characteristics. Close observation of the silhouette of the lower half of the body (from photographs taken from eight directions) revealed projecting parts, other than the hip line, that affected the circumference of the lower half of the body. Morphological factors that characterized body form were found by factor analysis of the data of the positional relations between transverse sections obtained by the sliding gauge method and the laser method. We were able to differentiate and classify body form characteristics by these morphological factors.
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  • Eisaku MURASE, Naoko TSUBOMIZU, Fumio SUGATA
    1989 Volume 49 Issue 5 Pages 471-479
    Published: October 28, 1989
    Released on J-STAGE: November 19, 2010
    JOURNAL FREE ACCESS
    The oral taurine loading test was conducted in patients with chronic hepatitis (CH), compensatory liver cirrhosis (CLC), decompensatory liver cirrhosis (DLC) and primary biliary liver cirrhosis (PBC), as well as in healthy volunteers, to evaluate changes in bile acid levels in patients with various hepatic diseases treated with taurine. Changes in blood bile acid levels, serum total cholesterol, and phospholipid were observed. Serum total bile acid levels (TBA) were significantly higher in patients with CLC, DLC and PBC than in healthy volunteers, but no effect of taurine loading was noted. The G/T ratio decreased significantly after taurine loading in patients with CH, CLC and PBC, and in healthy volunteers. In patients with DLC, however, the G/T ratio remained unchanged after taurine loading, suggesting that taurine conjugation is decreased in hepatocytes in these patients. The CA/CDCA ratio was higher in patients with PBC than in other patients, but no specific effect of taurine loading was noted. Taurine loading had no particular effect on serum total cholesterol or phospholipid. In conculusion, changes in the G/T ratio differed significantly according to the type of hepatic disease after taurine loading, suggesting that the oral taurine loading test is somewhat useful in determining pathology of hepatic diseases.
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  • —IN RELATION TO ENVIRON-MENTAL TEMPERATURE—
    Takeshi KUSUMI, Kashie ISHII, Mari KUSUMI, Keiko ARAI, Fumio ISHIZAKI, ...
    1989 Volume 49 Issue 5 Pages 480-487
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The temperature of the nasal skin is related to nasal symptoms ; the temperature of normal noses is lower than that of surrounding regions, whereas temperature of noses with obstruction or hyper-rhinorrhea is higher, and becomes more homogeneous with the surrounding regions. This phenomenon can be explained by one of the functions of the nose ; the warming of inhaled air, which eventually cools the nasal mucosa. This phenomenon is further revealed by comparing skin temperature with ambient temperature in each season, and by analyzing change of skin temperature during and after rapid increase of room temperature with and without cotton plugs in the nasal cavity. The following results were obtained. The skin temperature of normal noses increased with ambient temperature rise. The temperature of obstructed noses, however, remained high despite seasonal temperature changes. In the second experiment, the nasal skin temperature followed even small increase of room temperature, approaching the forehead skin temperature. In the third experiment, cotton plugs in the nose caused temperature to rise, and this returned to the initial temperature after removing the cotton. Through out the above experiments the skin temperature of the forehead was almost constant. This suggests that the temperature of nasal skin can reveal nasal signs as well as the ambient temperature.
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  • —A COMPARATIVE STUDY OF THE EFFECTS OF MOXIBUSTION, ELECTROACUPUNCTURE, AND KAMPO-HOZAI OHRENGEDOKUTOH ON DELAYED TYPE HYPERSENSITIVITY (DTH) IN MICE—
    Takako KASAHARA, Yu-Xing WU, Ye WANG, Yoshiko SAKURAI, Katsuji OGUCHI
    1989 Volume 49 Issue 5 Pages 488-495
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We report here effects of moxibustion, electroacupuncture and kampo-hozai on delayed type hypersensitivity to picryl chloride (PC) . Six-nine-week old male ddY mice were used. Stimuli were applied to the point equivalent to the Mingmen point of the human body (on the post median line, between the 2 nd and 3 rd lumbar spinal processes), which Chinese medicine regards to be closely related to immunity. Significant enhancement of ear swelling was observed when moxibustion (10 mg moxa/mouse) and electroacupuncture (2.5 Hz, 15 min.) were applied for three days before PC sensitization. Significant inhibition of ear swelling was observed when moxibustion, electroacupuncture (5 Hz, 10 min.) and oral administration of kam-po-hozai ohrengedoku-toh (made in our laboratory) were applied for three days before PC cha-llenge. Immunological responses occured in the peripheral blood monocyte fluctuation and cervical lymph nodes. Oriental medical treatment was proven to affect cellular immunization. Moxibustion and electroacupuncture either enhanced or inhibited immunological responses, depending on the time of treatment, and ohrengedoku-toh inhibited these responses.
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  • Kazuhide KUMAGAI, Akira YASUI, Yoshiaki NISHIDA, Yutaka SANADA, Koki M ...
    1989 Volume 49 Issue 5 Pages 496-500
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The purpose of this study was investigation of the characteristics of gastric carcinoma in the aged, older than 70 years. We made a comparative study of gastric carcinoma in the aged and that in patients younger than 70. There were 26 cases of gastric carcinoma in the aged in our institution, an incidence of 13%. The results were as follows: 1) Macroscopical type-The frequency of elevated early carcinoma was greater than in younger patients. 2) Size of lesion—Smaller size, early carcinoma (less than 2 cm diameter) occurred more often in younger patients. 3) Histological type—Most were differentiated type. 4) Location—Occur-rence in the lower part of the stomach predominated. 5) Surrounding gastric mucosa-The pyloric gland zone was dominant.
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  • Keiich MIYASAKA, Toyohiko HISHIDA, Masazumi ISHIKAWA, Kiyoshi KOZASA
    1989 Volume 49 Issue 5 Pages 501-504
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Seventy three patients with peptic ulcer associated with visible vessel were observed. Dieulafoy's ulcer was excluded. Peptic ulcers with visible vessel were noted in 40-59 year old males, and 50-69 year old females. Subjective symptoms of gastric ulcer were hematemesis, melena and abdominal pain in order. In the cases of duodenal ulcer, they were melena, abdominal pain, nausea and vomiting, in that order. The subjective symptoms were more severer than in peptic ulcer without visible vessel. The peptic ulcers were frequently found in the posterior wall of the upper body in the stomach, the lesser curvature of the lower body, and the posterior wall of the lesser curvature at the gastric angulus. The visible vessels were noted in the center of the ulcer crater at the angulus. In the ulcer craters in the gastric body, they were observed in the posterior wall on the oral side. In the ulcer craters in the duodenum, they were observed in the anterior wall on the oral side.
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  • Hiroshi NAKANO, Kimio NAMATAME, Tadatsugu HIROSE, Naoto HAMAI, Eiichi ...
    1989 Volume 49 Issue 5 Pages 505-509
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The incidence of double cancers of the stomach and cholangio-pancreatic system is relatively low. Little has been reported on cases of double cancer of the stomach and papilla of Vater, especially of time-sharing double cancer. Recently, we operated on time-sharing double cancer of the stomach and papilla of Vater. The patient was a 70 year old man who had had subtotal gastrectomy due to Borrmann type 1 gastric cancer, in March, 1982. During postoperative follow up, near the end of November, 1985, a yellowish change in skin was noted and he visited our hospital. In the biochemical analyis, the total-bilirubin was 12.3 mg/dl. After admission, PTCD was performed and abnormal papillary lesion was revealed. Endoscopic examination revealed carcinoma of the papilla of Vater. In January, 1986, pancreaticoduodenectomy was performed. Examination of the rescted preparation showed histological depth of invasion to the Oddi muscle.
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  • Hiroshi NAKANO, Kimio NAMATAME, Toyohide NAKAMURA, Youmo KOH, Tadatsug ...
    1989 Volume 49 Issue 5 Pages 510-514
    Published: October 28, 1989
    Released on J-STAGE: November 19, 2010
    JOURNAL FREE ACCESS
    An 83-year-old woman was admitted to our hospital for operation on a small elevated lesion of the esophagus. Endoscopic examination revealed a small (about 1 cm) abnormal elevated lesion of the esophagus. The lesion was diagnosed by endoscopy as a superficial, elevated type of esophageal cancer. Biopsy showed moderate differentiated squamous cell carcinoma. From endoscopic ultrasonographic findings, the invasive depth of the lesion was diagnosed submucosa, and no lymphnode metastasis was evident. Her advanced age and respiratory disfunction contraindicated radical operation, and we elected combined modality therapies, composed mainly of endoscopic therapy. We performed endoscopic laser therapy, radiation therapy, PANa oil BLM peroral contact therapy, and OK 432 local injection therapy, but complete histological response was not achieved. Finally we performed endoscopic palliative intubation to improve her disphagia. She died because of excess hematoemesis. Of her 2 years and 2 months duration clinical course, house medical care was 17 months. She achieved good performance status during her clinical course.
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1989 Volume 49 Issue 5 Pages 515-520
    Published: October 28, 1989
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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