Abstract
The serial change of serum lipids were examined in patients with laparotomy suffering from gastric cancer. The patients were classified into two groups by their nutritional condition : one was enteral nutrition, and the other was parenteral nutrition. In the enteral nutrition group, pre-operation serum cholesterol of 206.7±31.9 mg/dl, dropped to 135.9± 26.1mg/dl on 3 days after the operation. The cholesterol then increased gradually, and recovered to 73.8 % of the pre-operation value 14 days after the operation. Pre-operation cholesterol of 155.0±32.0 mg/dl in the parenteral nutrition group dropped to 106.7±24.5 mg/dl, and then recovered rapidly to 153.5±29.0 mg/dl 14 days after the operation. Serum free cholesterol and phospholipid changed in almost the same way. The serial change of serum HDL-cholesterol was different from that of serum cholesterol. In the enteral nutrition group, the pre-operation value decreased gradually to the lowest value of 32.3±12.1 mg/dl 7 days after the operation. The degree of decrease in the parenteral nutrition group, was smaller than that in the enteral nutrition group. The pre-operation value of 35.6+11.0 mg/dl dropped to 30.2±7.6 mg/dl and recovered to 93.5 % of the pre-operation value 14 days after the operation. The changes of apo-A-I in the two groups were almost the same way as that of serum HDL-cholesterol in each group. The number of cases in which intermediate low density lipoprotein (IDL) increased after the operation were : 2 of 15 cases at pre-operation to 10 of 15 cases at 7 days after operation in the enteral nutrition group ; and 4 of 18 at pre-operation to 6 of 18 7 days after operation in the parenteral nutrition group.
