Abstract
The incidence and the pathogenesis of gastritis cystica polyposa (GCP), which occurred at a site of gastric anastomosis, were investigated. The subjects were 112 patients with partial gastrectomy by Billroth- I (Bill- I) or Billroth- II (Bill- II) for benign gastric diseases or duodenal ulcers. GCP was observed in patients operated by either Bill-I or Bill-II. Although there was no correlation between the incidence of GCP and postoperative period in the patients operated for benign gastric diseases, its incidence increased with elongation of the postoperative period in the patients operated for duodenal ulcer. The duodenal ulcer patients were younger than the patients with gastric diseases, so aging of the stomach or atrophic change may contribute to the development of GCP. There were no significant differences in trypsin concentration in the gastric juice or mucosal content of hexosamine between the patients with and without GCP. CDCA and CA concentrations in the gastric juice were significantly higher and glycine/taurine conjugation ratio was significantly lower in the patients with GCP. This suggests the bile acid influences on the development of GCP. However, CDCA and CA concentrations in the patients without GCP operated by Bill- II was much higher than that in patients with GCP operated by Bill- I, so it is suggested that changes of bile acids must be a factor in the development of GCP and other factors were involved in the patients operated by Bill-II.
