Abstract
A rare case of acute hepatitis B accompanied by acute renal failure was reported. A 46-year-old male with pyrexia, general fatigability and vomiting was transferred to our hospital because of the development of renal failure with liver injury. On physical examination, jaundice and petechiae on the lower extremitits were noticed, but consciousness was clear. High serum levels of GOT, GPT, bilirubin, BUN and creatinine, decreased prothrombin activity, and positive studies for HBs antigen and IgM HBc antibody were shown on laboratory examination and a diagnosis of acute hepatitis with renal failure was made. Encephalopathy did not develop during the clinical course and hepatic and renal injuries were improved uneventfully by hemodialysis, plasmapheresis and glucagon insulin therapy. Acute hepatitis B except fulminant hepatitis is rarely accompanied by acute renal failure and possible mechanisms are discussed.
