Abstract
In August 1991 a 59-year-old man was admitted to our hospital with a chief complaint of epigastralgia. Endoscopic examination revealed a protruding lesion with a bridging fold and ulceration in the posterior wall of the antrum. This lesion was suspected to be gastric carcinoma showing features of a submucosal tumor, but histologic examination of a endoscopic biopsy specimen revealed no malignancy. One month, 2 months, and 6 months later, the ulceration healed and the lesion protruded less. In June 1994 this lesion took the form of two fused submucosal tumors. Histologic examination of an endoscopic biopsy specimen revealed gastric carcinoma. Distal gastractomy was performed. Pathologic examination revealed poorly differentiated adenocarcinoma with increased collagen fibers in the submucosa. A case of gastric carcinoma with features of submucosal tumor and histologic change over 3 years is reported.
