Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 56, Issue 5
Displaying 1-14 of 14 articles from this issue
  • [in Japanese]
    1996 Volume 56 Issue 5 Pages 485-496
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • —Comparison of effectiveness and safety—
    Kazumi CHIYODA, Youichi KOBAYASHI, Akira MIYATA, Haruyuki NAKAGAWA, Ka ...
    1996 Volume 56 Issue 5 Pages 497-502
    Published: October 28, 1996
    Released on J-STAGE: November 19, 2010
    JOURNAL FREE ACCESS
    We studied the effectiveness and safety of radiofrequency catheter ablation (RF-Ab) for treatment of atrioventricular nodal reentrant tachycardia (AVNRT) . The subjects were 31 patients with AVNRT (12 men; mean age, 54±14 years) . All patients gave written informed consent. Quadripolar electrode catheters were placed via the left inguinal region in the apex of the right ventricle, the site of recording of the bundle of His electrogram, and the anterior wall of the right atrium. The ablation site was targeted for the slow pathway potential or the earliest atrial activation site, which is retrograde to the slow pathway. When both of above-described methods were unsuccessful, stepwise ablation was attempted by moving toward the site of recording of the bundle of His electrogram from the vicinity of the ostium of the coronary sinus. After ablation, AVNRT was not inducible in any patient. Transient IIIrd degree atrioventricular block was observed in one patient. First degree atrioventricular block was also observed in one patient. Only one patient needed to undergo ablation again because of recurrence of tachycardia 18 months after the first ablation. RF-Ab is an effective therapy for AVNRT. However, we should treat the cause of dysfunction of atrioventricular nodal conduction treated by RF-Ab.
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  • Tadashi ISHIKAWA, Susumu OONAGI
    1996 Volume 56 Issue 5 Pages 503-510
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The lip is an anatomic element that contributes to the creation of the impression of individual facial features. The aim of the present study was to elucidate the morphology of the lip by measuring the area of lip and face and to evaluate the shape of lips in terms of areal and circularity ratios. In this study, the author analyzed the morphology of the lip at rest in 107 healthy young Japanese women (mean age, 22.3 years) and measured and calculated several parameters as follow: (1) perimeters and areas of both lips, upper lip, lower lip, and face, (2) ratios of total lip area to facial area, upper lip area to facial area, and lower lip area to facial area, (3) circularity ratios of the face, both lips, upper lip, and lower lip. The mean areas of the face, both lips, upper lip, and lower lip were 19440.8 mm2, 598.00 mm2, 223.63 mm2 and 374.37 mm2, respectively. The mean ratios of total lip area to facial area, upper lip to total lip area, and lower lip to total lip area were 3.076 %, 1.15 %, and 1.9 %, respectively. The mean circularity ratios of the face, both lips, upper lip, and lower lip were 0.940, 0.677, 0.335, and 0.462, respectively. In the present study, we found a relation between the shape of the lip and the circularity ratio. This sort of evaluation may be effective in understanding sex differences, aging processes, various diseases related to the lip, and preoperative and postoperative differences.
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  • Hiroyuki SATOH, Masaru TATSUNO, Youji IIKURA, Yuji KIUCHI
    1996 Volume 56 Issue 5 Pages 511-516
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We studied the effects of hypoxia and ischemia-hypoxia on extracellular levels of amino acids (aspartate, glutamate, glutamine, taurine, and alanine) in the striatum of neonatal rats using the microdialysis method. After insertion of a microdialysis probe in the striatum, 7-day-old rat pups were exposed to 8% or 5% O2 for 120 minutes or to 8% O2 for 120 minutes following ligation of the bilateral carotid arteries. Amino acid levels in striatal dialysates collected every 20 minutes were measured with high-performance liquid chromatography and a electrochemical detector. There were no significant changes in glutamate or aspartate levels in dialysates during hypoxia or hypoxia-ischemia. On the other hand, taurine levels were significantly higher during 5% O2 exposure than in control rats. Alanine levels were significantly higher in all hypoxia and ischemia-hypoxia groups. These data suggest that low susceptibility of excitatory amino acidergic neurons during hypoxia or ischemia or both might be involved in the resistance of immature brain against these events.
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  • Kentaro NAKAO, Miki SHIBUSAWA, Akira TSUNODA, Kenshi HIRATSUKA, Gouich ...
    1996 Volume 56 Issue 5 Pages 517-521
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Using the labeling index of proliferating cell nuclear antigen (PCNA), we performed a clinicopathological study of 21 villous adenomas of the large bowel. Patients were 12 men and 8 women (mean age, 67.2 years) . Most tumors were located in the sigmoid colon. Large tumors tended to be villous adenoma with carcinoma, of which 61.9% had invaded the mucosa or submucosa. In villous adenoma with carcinoma, the PCNA labeling index in areas of villous adenoma and areas of carcinoma differed. However, there was no difference in the labeling indices of areas of villous adenomas with and without carcinoma. In this study most PCNA-positive cells were in focal areas of dysplasia. When colonoscopic biopsy is performed, taking specimens from areas of carcinoma is not necessary. However, when a tumor is diagnosed as villous adenoma, many biopsies must be performed. In addition, we must investigate villous adenomas on the basis of results of biopsies and other factors, such as tumor diameter.
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  • A DOUBLE-BLIND, CROSSOVER, PLACEBO-CONTROLLED CLINICAL TRIAL
    Michio HOSAKA, Yoshiharu HOSHIYAMA
    1996 Volume 56 Issue 5 Pages 522-529
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Home oxygen therapy (HOT) can improve survival rates of patients with chronic reppiratory insufficiency but may also lower a patient's quality of life (QOL) owing to limitations on patient's daily living and social activities because of the difficulties in handling the equipment. Thus, the ability of diazepam to improve QOL of patients receiving HOT, was evaluated in a double-blind, crossover, placebo-controlled clinical trial.
    Subjects were patients with type 1 respiratory insufficiency that was stable after 3 months of HOT. After informed consent was obtained, patients were given diazepam (0.1 to 0.2 mg/kg) or a placebo once a month for 4 months. Psychologic tests were performed before adminstration to assess character and personality, and physical and mental examinations were performed at the beginning and end of each month.
    Diazepam significantly reduced dyspnea without producing side effects, such as respiratory depression. Depression and anxiety tended to decrease in patients given diazepam but tended to increase in patients given placebo. Patients' QOL, as measured by the sickness impact profile, and mental function also tended to improve in the diazepam group and worsen in the placebo group. However, these differences were not statistically significant, probably because a low dose of diazepam was given owing to possible respiratory depression. Discriminant analysis suggested that diazepam had a greater effect in patients who had more severe dyspnea and some character types of Minnesota Multiphasic Personality Inventory and the Y-G character test.
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  • Hirohide TAKAHASHI, Yoshihiro WAKAYAMA
    1996 Volume 56 Issue 5 Pages 530-534
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The onset of Parkinson's disease is so gradual that most patients find it impossible to define precisely when the disorder began. While abnormalities of motor function are usually the reason for initial contact with physicians leading to the diagnosis of Parkinson's disease, certain ‘preclinical’features preceding the motor signs may be noticed by the patient. To clarify what these‘preclinical’features may be and when they may start, we conducted a survey by questionnaire of 54 patients with Parkinson's disease. Seventeen patients had subtle features, such as“stiffness, ”“numbness, ”and“writing difficulties”in a limb or shoulder ipsilateral to the initial motor deficit. Two patients had‘preclinical’features for 12 years or more, a finding that suggests compensatory periods may be this long.
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  • Tomiaki IKEDA, Jun MANABE, Kazuyuki SERADA, Teruaki TOMARU
    1996 Volume 56 Issue 5 Pages 535-537
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We report a case of atypical facial pain, which was initially diagnosed as trigeminal neuralgia at another outpatient department. A 69-year-old woman complained of pain on her right infraorbital area. The pain in the face of which the patient complained did not seem to be consistent with symptons of trigeminal neuralgia, therefore, we diagnosed her facial pain as atypical facial pain based on her history and physical examination. The patient was treated with stellate ganglion block once a day for 20 days and infraorbital nerve block once on her 1st hospital day. On her 2nd hospital day, her pain did not progress and on her 20th hospital day, her facial pain was relieved. We confirmed that stellate ganglion block and infraorbital nerve block were effective for treatment of atypical facial neuralgia.
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  • -The Pitfall of Medical Examination : Case Report-
    Kazuo HANAKAWA, Hisato IKEDA, Teru KAWAMATA, Takanobu IWATA, Kiyoshi M ...
    1996 Volume 56 Issue 5 Pages 538-541
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We report a case of ruptured aneurysm with subarachnoid hemorrhage (SAH) in an elderly patient. An 89-year-old man suffered from disturbance of consciousness and was admitted to our hospital. He had been operated on for bilateral chronic subdural hematomas 6 months before. He suffered from headache both before and during admission. His consciousness was rated 10 by the Japanese coma scale, and he showed right hemiparesis. A computed tomographic scan revealed left chronic subdural hematomas with a depressed frontal lobe. The left Sylvian fissure was unclear. On reviewing the course of the illness, we suspected subarachnoid hemorrhage. Cerebrospinal fluid samples obtained at lumbar puncture showed xanthochromia. Therefore, SAH was diagnosed. All treatment was refused by the family. Four days later, the patient's consciousness level worsened to coma and the patient expired. A computed tomographic scan revealed reformation of SAH.
    Recently, average life-spans have been increasing along with the number of elderly people. Thus, the chance of encountering a ruptured aneurysm in elderly patients is also increasing. When we undertake physical examinations of elderly patients, we consider it essential to understand the background of each patient and their chief complaints without being influenced by their past history.
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  • Nobuo KOMATSU, Kazushige ARAI, Masatoshi KAWAMURA, Hiroshi ISHII, Moto ...
    1996 Volume 56 Issue 5 Pages 542-546
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    In August 1991 a 59-year-old man was admitted to our hospital with a chief complaint of epigastralgia. Endoscopic examination revealed a protruding lesion with a bridging fold and ulceration in the posterior wall of the antrum. This lesion was suspected to be gastric carcinoma showing features of a submucosal tumor, but histologic examination of a endoscopic biopsy specimen revealed no malignancy. One month, 2 months, and 6 months later, the ulceration healed and the lesion protruded less. In June 1994 this lesion took the form of two fused submucosal tumors. Histologic examination of an endoscopic biopsy specimen revealed gastric carcinoma. Distal gastractomy was performed. Pathologic examination revealed poorly differentiated adenocarcinoma with increased collagen fibers in the submucosa. A case of gastric carcinoma with features of submucosal tumor and histologic change over 3 years is reported.
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  • 1996 Volume 56 Issue 5 Pages 547-550
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • 1996 Volume 56 Issue 5 Pages 551-560
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1996 Volume 56 Issue 5 Pages 561-565
    Published: October 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1996 Volume 56 Issue 5 Pages 566-568
    Published: October 28, 1996
    Released on J-STAGE: November 19, 2010
    JOURNAL FREE ACCESS
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