2002 Volume 62 Issue 4 Pages 248-253
A 44-year-old man complained of lumbago and was treated with on intramuscular analgetic injection by a doctor near his house. Because of a hematoma, which was recognized in the injection site, as well as a fever, further examinations were carried out, and finally disseminated intravascular coagulation (DIC) and bone marrow necrosis were revealed. The patient received treatments of DIC as well as examinations to determine the causes of bone marrow necrosis. However, the causes were not determined because he died the 8th day after admission due to worsening general conditions. Autopsy findings revealed primary advanced gastric cancer in the antrum and multiple metastatic foci in the bone marrow. Histopathologic diagnosis showed poorly differentiated adenocarcinoma associated with signet-ring cell carcinoma. We report here not only an autopsy case of bone marrow necrosis, the cause of which was unknown until an autopsy, but also the review of the literature concerning bone marrow necrosis.
