Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
A FATAL CASE OF CHURG-STRAUSS SYNDROME WITH RECURRENCE OF VASCULITIS SYMPTOMS DURING CORTICOSTEROID TAPERING
Takashi KATSURAYoshinao KATAOKAShin INOUEKazumasa TANAKAFumihide YOSHIDAToshiyuki TAZAKIMayumi KATSURAMitsuru ADACHI
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2003 Volume 63 Issue 5 Pages 497-500

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Abstract
We report a fatal case of a 71-year-old man who had Churg-Strauss syndrome with recurrence of vasculitis symptoms during corticosteroid tapering. Because the patient had bronchial asthma, eosinophilia, and vasculitis symptoms, a diagnosis of Churg-Strauss syndrome was made. We commenced the administration of 1 mg/ kg / day of prednisone. The oral corticosteroid treatment was continued for 1 month. Subsequently, the treatment was tapered because no evidence of disease was present. The patient, however, died of recurrence and exacerbation of vasculitis symptoms during a gradual taper of prednisone. Thus, we believe that physicians who treat patients with Churg-Strauss syndrome should always guard against a severe relapse of vasculitis and prepare to commence methylprednisolone pulse treatment or additional therapy of immunosuppressive agents during a taper of corticosteroid.
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