Abstract
The effects of Gaiyo (G), Juyaku (J) and Sasa Cu-Chlorophyll extracted remnants (SCER) on oxazolone (Oxa) -induced allergic dermatitis in BDF1 mice were investigated. Ear swelling of Oxa-induced allergic dermatitis was produced following form application of Oxa in BDF1 mice. SCER-G and SCER-J reduced Oxainduced ear swelling. Oral administration and application of SCER-GJ inhibited ear swelling, hemorrhaging and incrustation in Oxa-induced allergic dermatitis. According to histopathological examination of the auricle in each group, the incrustation, hypertrophy of epidermis and dermis and increases of mast cells in Oxa-induced dermatitis were inhibited by SCER-GJ administration. These results suggest that SCER-GJ improvs allergic dermatitis and atopic dermatitis.
