生体医工学
Online ISSN : 1881-4379
Print ISSN : 1347-443X
ISSN-L : 1347-443X
研究
イオン泳動効果のMRIテンソル表示
疋島 啓吾本間 一弘早水 紀久子相原 雄一沼野 智一新田 尚隆八木 一夫
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2007 年 45 巻 4 号 p. 292-297

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The goal of this study is to make active or passive electrical characteristics of biological systems visible by magnetic resonance imaging (MRI). As a starting investigation, we visualized a precise flow effected by ionophoresis. We used CuSO4 doped water (25 mM) electrolytes in an ionophoresis cell composed of a pair of horizontal copper electrodes. An evaluation of ion drift, we made by MR diffusion tensor imaging method. The impressed voltage was 0.0-0.5 V, and the current density at that time increased monotonously was 0.00-1.06 mA/cm2. With increasing current density, higher values of drift diffusion coefficient (DDC) induced by the electric field were observed.
The diffusion tensor ellipsoid in current density of 1.06 mA/cm2 was successfully visualized as the effects of ion drift induced by the electric field. By applying this method to biological systems, it has a possibility to make functional electrical characteristics visible.
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© 2007 社団法人日本生体医工学会
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