一般演題（口演）
ヒトiPS細胞由来ニューロンの機能センシング技術の開発
2014 年 52 巻 Supplement 号 p. O-190-O-191
詳細
2014 年 52 巻 Supplement 号 p. O-190-O-191
Neuronal cells can be generated from Human induced pluripotent stem cells (hiPSCs), providing a very important alternative to studies of humans and model organisms, to facilitate a better understanding of the mechanisms of neurological diseases and identifying novel therapeutic avenues. However, the functional assays of cultured human iPSC-derived neurons have not been established. Here, we have developed the noninvasive and real-time cell sensing techniques of three fundamental function (1) action potential, (2) neurotransmitter release, and (3) post synaptic potentials. These techniques may be beneficial for clarifying the functions of human neuronal circuits and for drug screening applications.
