Abstract
According to the progress of genome sequencing technology, the cost of genome analyses is rapidly decreasing, and the feasibility of genome-based personalized healthcare is dramatically increasing. Actually, a lot of large-scale genome cohort studies are established to realize personalized healthcare. Tohoku University is also constructing a new genome cohort in the process of constructive recoveries from the Great East Japan Earthquake on March 11, 2011. On the other hands, the cost of information analyses of genome data is not decreased, mainly due to the increase of the amount of data produced by new generation sequencers and high sensitivity of the data. In this talk, I will introduce our approaches to build a basis of in-silico analyses though the setup of a new computer system in Tohoku Medical Megabank, and discuss some issues in information analyses to realize the genome-based personalized healthcare.
