A new therapeutic strategy for chronic atrial fibrillation: Development of the real-time phase mapping system using in silico technique

Abstract

Rotor ablation has been proposed as the effective treatment for human atrial fibrillation (AF). However, existing mapping systems usually take too much time to visualize activation sequences.Methods: We have developed a novel real-time phase mapping system called “ExTRa Mapping” to detect unstable rotors during AF. Based on bipolar signals of a 20-pole spiral-shaped ring catheter, action potential temporal dynamics was numerically estimated. Results: Unstable rotors during in silico AF were reconstructed by ExTRa Mapping (Fig). ExTRa Mapping could identify unstable rotors during clinical AF by creating phase maps on a real-time basis.Conclusion: ExTRa Mapping could open a new avenue for identifying unstable rotors during AF ablation.