Abstract
Oxygen availability in the cell defines physiology and pathophysiology of cellular functions. Although measurement of Po2 in arterial blood using oxygen electrode is already well-established, the measurement permits assessment of cellular oxygen only incompletely because the considerable gradient in oxygen concentration is present between arterial blood and intracellular space that varies according to the tissue blood flow, tissue vasculature geometry, and cellular oxygen demand. Therefore, we are prompted to directly measure the level of oxygen as it works in the cell. At present, however, not many techniques are available for accurate assessment of cellular oxygenation, particularly in vivo. In this session, actively working researchers in this field will introduce recent techniques for tissue oxygen measurement in vivo. I, the organizer, have asked the speakers to explicitly specify the following; parameter measured, spatial resolution, time resolution, resolution in oxygen concentration, perturbation caused from the measurement, and limitation of the measurement. We hope that the information provided here give a clue to optimize your oxygen measurement.
