Transactions of Japanese Society for Medical and Biological Engineering
Online ISSN : 1881-4379
Print ISSN : 1347-443X
ISSN-L : 1347-443X
Proceedings
Computational fluid dynamical approach for thrombus formation
MASAAKI TAMAGAWATakanori YoshikawaWeiwei Shi
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2015 Volume 53 Issue Supplement Pages S134_03

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Abstract
To avoid the thrombus in artificial organs, especially rotary blood pumps and heart valves, it is necessary to understand the fundamental physical mechanism for thrombus formation on shear flows. The mechanism of thrombus formation is complicated because it includes biochemical factors. The main physical factors of thrombus formation are considered to be shear stress (shear rate), wall properties for blood's adhesion and transport process of aggregation factor in the flow. In spite of this complicacy, it is preferable for mechanical engineer to design the devices using the simple prediction tool such as CFD software. Concerning about CFD method, we have proposed two CFD approaches such as finite volume method (FVM) and lattice Boltzmann method (LBM) to predict thrombus formation.In this presentation, to establish the prediction method for thrombus formation by this CFD (FVM), the orifice flow with simple geometry and separation and reattachment flow as seen in the blood pumps is used for analysis. The CFD results are compared with the experiments to validate this prediction method by CFD.
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© 2015 Japanese Society for Medical and Biological Engineering
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