Abstract
Time resolved spectroscopy (TRS) allows us to measure absolute values of hemoglobin (Hb) concentrations at rest. We evaluated reliability of TRS measurements of brain function. At first, we compared Hb concentrations of the frontal lobe in the morning, noon, and evening in 16 normal young adults, and found no significant difference between the times. Then, we evaluated the relation between SO2 in the frontal lobe and cognitive function measured by Mini Mental State Examination (MMSE) in 22 middle-aged people and seniors, and found significant positive correlation between them (Fig.1). These results suggest that TRS may be a useful tool for assess the cognitive function.
