抄録
We have been developing an optical system for monitoring urinary substances. In this study, we carried out preliminary experiments for estimating concentration of four urine substances, i.e., glucose(Glu), urea(Ur), sodium chloride(NaCl), and creatinine(Cr) using an FT-IR spectrometer.The samples used were random urine collected from a male adult suspicious of having diabetes. Altogether 21 samples were obtained and concentration of the four substances in these samples were determined by standard clinical chemistry assays. On the other hand, absorption spectrums were measured by the spectrometer with the wavelength of 750-2500nm (1750 data) and the PLS was applied for analysis. From the results obtained, it was confirmed that, by using not all of the 1750 data, but using the 236 selected data based on concentration dependent wavelength, high accuracy in estimating concentration of the four substances were attained (correlation coefficient, Glu: 0.991, Ur: 0.992, NaCl: 0.951, Cr: 0.709). We are still trying to reduce the number of the wavelength, e.g., less than ten, used for data analysis considering the practical use, and the results of this attempt will be also presented. (179words)
