2016 Volume 54Annual Issue 26AM-Abstract Pages S20
We report on a study for constructing a multi-scale statistical model of pancreatic cancer with its mechanical characteristics. The model is constructed from images captured from KPC mice: Temporal series of MR images captured during the progress of their pancreatic cancers, micro CT images of the extracted pancreases, and their microscopic images. In addition, we measure the mechanical characteristics when we extract the pancreases from the mice. We need to register these images of different modalities together in order for the construction of the model. For registering the microscopic images and the MR ones, of which the spatial resolutions are seriously different, we firstly register the 2D microscopic images together to construct a 3D microscopic image from them, then register the 3D microscopic image with the micro CT image that has the intermediate level of the spatial resolution, and finally register the micro CT image with the MR images.