Transactions of Japanese Society for Medical and Biological Engineering
Online ISSN : 1881-4379
Print ISSN : 1347-443X
ISSN-L : 1347-443X
Proceedings
Multiscale function and pathology modeling of digestive system
Hidekata HontaniAkinobu ShimizNaoki KobayashiHayaru ShounoChika IwamotoKenoki OhuchidaMakoto HashizumeEtsuko Kobayashi
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2016 Volume 54Annual Issue 26AM-Abstract Pages S20

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Abstract

We report on a study for constructing a multi-scale statistical model of pancreatic cancer with its mechanical characteristics. The model is constructed from images captured from KPC mice: Temporal series of MR images captured during the progress of their pancreatic cancers, micro CT images of the extracted pancreases, and their microscopic images. In addition, we measure the mechanical characteristics when we extract the pancreases from the mice. We need to register these images of different modalities together in order for the construction of the model. For registering the microscopic images and the MR ones, of which the spatial resolutions are seriously different, we firstly register the 2D microscopic images together to construct a 3D microscopic image from them, then register the 3D microscopic image with the micro CT image that has the intermediate level of the spatial resolution, and finally register the micro CT image with the MR images.

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© 2016 Japanese Society for Medical and Biological Engineering
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