2016 Volume 54Annual Issue 26AM-Abstract Pages S22
Due to increasing interest to healthy life expectancy, the significance of the musculoskeletal system is recognized more than before. In addition to medicine, musculoskeletal anatomy is related to sports science, art, computer graphics and so on. In this talk, anatomy-based multiscale function and pathology modeling of the musculoskeletal system is presented, which is under development in the "Multidisciplinary Computational Anatomy" project. This model consists of mathematical and statistical models on bone-muscle relations, muscle fibers, bone orientations at the standing position, articular motions, and bone micro-structure from the aspect of function, as well as deformations due to osteoarthritis from the aspect of pathology. This model is constructed from clinical CT database and other modality data, including micro-CT, histology, X-ray, ultrasound images, and so on. Fundamental technologies for representation and construction of the model are presented and its applications to segmentation, muscle fiber modeling, and computer-aided diagnosis and therapy are overviewed.
