Effect of Hybrid Interface Control on Mechanical Properties of HAp/PCL Composite Materials for Bone Regeneration

Abstract

In order to optimize bone regeneration, it is necessary to improve the performance of bio-absorbable materials, which act as substitution of bone function and scaffold of bone formation. We had tried to improve mechanical properties of HAp/PLA composite materials by the hybrid interface control using both chitosan and pectin and the control of interface control ratio. However, since the degradation speed of PLA is low, it is concerned that HAp crystals under the degradation state might remain without being absorbed. Therefore, we aimed to verify the applicability of the hybrid interface control and the control of interface control ratio to HAp/PCL composite materials, which can enable the acceleration of absorption utilizing osteoclastic metabolic behavior. As results of FT-IR measurement and tensile test, the fracture strain of HAp/PCL was significantly improved in the case of 100% of interface control ratio