In this study, a multi-point LDV was developed to improve upon the near infrared laser Doppler flow velocity distribution device for the purpose of non-invasive measurement of in vivo blood flow state. Using the special features of this device, when a follow-up exam was performed on a mouse ear that had undergone a melanoma transplant, it was confirmed that there had been a reduction in the melanoma. It is known that cancer cells can be killed at 40 degrees centigrade, so we believe that the temperature increase at the laser intersection is the cause of the reduction in the melanoma. Therefore, the MLDV that was used in this research is now being considered for use in cancer treatment. The temperature rises of biological tissue when measured at various irradiation depths was announced, and there was a debate regarding the possibility of the use of this device in curative treatment.
