2017 Volume 55Annual Issue 3AM-Abstract Pages 169
An agenda of the ventricular assist devices is the clot formation, to cause cerebral infarction. The clot formed at the boundary between artificial materials and the living body. We were tried to develop new medical material by regenerating biotissue into the artificial material. In this report, we develop new inflow cannula use with hybrid material, and observed concrescence about heart and hybrid material. The scaffold was implanted under the skin and the biotissues ware regenerated into the scaffold. The hybrid cannula was made with this hybrid material, and evaluate it use with helical flow ventricular assist device by animal experiment. After 3 month, the cannula was fused with cardiac muscle smoothly. Any clot was observed on the surface of the hybrid material and gap between heart and the material. Endocapillary cell was observed surface of the material. These results show the usefulness of the medical material.