Simulation of various circulatory abnormalities with hybrid mock system and evaluation of control method

Abstract

A synchronized control of left ventricular assist devices has some advantages in comparison with constant rotational speed control. However, because a risk of occurrence of abnormal situation such as suction and regurgitation increase, the controller should adapt such abnormal situations. The aim of this study is to simulate the abnormal condition using hybrid-mock circulatory system combining computer simulator and mock circulatory system.Suction, regurgitation and deterioration of heart function were simulated in hybrid-mock circulatory system and the each behavior were compared with the results of animal experiments.As a result, it was confirmed that the abnormal situation simulated using the hybrid-mock circulatory system and each behavior was similar as the result of the animal experiment. Therefore, it is possible to investigate and evaluate the control algorithm using actual pump and controller.