Response Surface based Analysis to Improve the Intravascular Stent Design Performance on Optimizing Wall Shear Stress Conditions

抄録

Restenosis is known as common problem during stent treatment. Stent optimization has been introduced to find the best design criteria in order to improve the endovascular treatment efficacy. Surrogate method is known as efficient method of optimization that has been built up from finite element method (FEM) simulation. Besides obtaining the optimized criteria, response surface plot which constructed by Kriging surrogate estimation process is also beneficial to study the behavior of design variables towards objective functions. In this study, we constructed the response surface map from stent design parameter configuration of strut size and inter-strut gap towards objective function. Our objective function is to minimizing the percentage of low wall shear stress area along deployment region. With this response surface, broad analysis on the stent performance can be clearly observed. More recommendations on how combinations between stent strut’s size and gap should be designed are successfully obtained by this study.