Development of bioadhesive oxygen sensor using electrochemiluminescence

Abstract

Noninvasive continuous oxygen measurement in living bodies is important in clinics and basic experiments. Focusing on the phosphorescent-lifetime method which can measure the absolute value of the oxygen concentration, we developed a film type oxygen sensor. A thin oxygen sensing film was prepared by mixing Pd-meso-tetra(4-carboxyphenyl)porphyrin (Pd-TCPP) with Polydimethylsiloxane (PDMS). We report calibration experiments on oxygen partial pressure change by using electrochemiluminescenece (ECL) and LED (Light emitting diode) as light source and electrode characteristics for flexible substrate material.

AC voltage was applied to the light source, and the oxygen partial pressure was calculated from phase shift of the light source and phosphorescence.

As a result of calibration experiment, we could measure oxygen-partial-pressure with high accuracy by LED. However, ECL excitation showed a phase shift, but measurement accuracy was lower than LED. We will improve the measurement accuracy by improving emission intensity and applied voltage pattern of ECL.