In-vitro experiment about Butterfly-shape artificial atrioventricular valve by using Biosheet

Abstract

We have been developing BioValve as an artificial hearts valve by using iBTA. Because atrioventricular valve has a complicated structure consisting of both leaflet and tendinous cords, and its performance is affected by the cord length, BioValve have not been applied to atrioventricular valve. The purpose of this study is a simple shape artificial atrioventricular valve developing. Newly developed valve consists of a metal annulus and a BioSheet. Because a BioSheet is fixed on a beam of the annulus, the sheet can open and close with flow change like a mechanical butterfly-valve. The valve performance, such as regurgitation-ratio, EOA and pressure-drop was measured by using arterial circulation simulator under the typical physiological conditions. To apply to optimal design, we had fabricated a valve model by using polyurethane sheet, of which mechanical bending properties were same as the BioSheet, and the influence of shape change of the leaflet was investigated.