Consideration of temperature distribution characteristics of ferromagnetic implant of hyperthermia

Abstract

We are investigating hyperthermia technology (soft heating method) that injects about 1 g of temperature-sensitive magnetic fine particles (implant) into the tumor and applies a high-frequency magnetic field from outside the body to locally heat the tumor. Past studies have reported a constant temperature heating system that can heat while monitoring temperature information non-invasively. However, the temperature distribution of the implant during the heating process when applying a high-frequency magnetic field was unknown.In this study, the temperature distribution inside the implant was measured with an optical fiber thermometer using the frequency and magnetic flux density of the applied magnetic field as parameters, and the heat generation unevenness was examined.