2020 Volume Annual58 Issue Abstract Pages 267
Artificial lung is a medical device for gas exchange composed of hollow fibers (HF). However, the HF membrane caused a plasma leakage attributed to pores on the membrane. To solve this problem, we suggest that the combination of homogeneous membrane and cross-linked 2-Methacryloyloxyethylphosphorylcholine (MPC) polymer. But there is no report in a paper on artificial lungs as the effect of the coating on gas permeability is unknown.The purpose of this study is to achieve both oxygen permeability and blood compatibility when a silicone surface is coated to a crosslinked phospholipid polymer. First, the effect of the MPC coated of silicone on oxygen permeability was evaluated. For the oxygen permeability test, an electrochemical method used. Sylgard184, one of the silicones, was confirmed to have an oxygen permeability coefficient of 358 barrer.
