2020 Volume Annual58 Issue Abstract Pages 300
Optical mapping method is a powerful tool for observing the cardiac excitation wave propagation. In this method, generally the measurement of action potential is performed on the assumption that the same pixel is continuously reflected on the same myocardium, but cardiac muscle must contract with depolarization. In general measurement, the measurement of myocardial movement was stopped using BDM or Cyto-D, one of the muscle contraction inhibitors, to suppress pulsation artifacts. However, BDM has been shown to affect cardiac electrophysiology such as shortening action potential duration and slow conduction velocity.In this study, we developed a system that visualization cardiac excitation propagation without BDM using offline image processing with Non-rigid registration and affine transform.
