Transactions of Japanese Society for Medical and Biological Engineering
Online ISSN : 1881-4379
Print ISSN : 1347-443X
ISSN-L : 1347-443X
Development and clinical application of personalized medicine and real-time pneumonia monitor
Masahiro KandaYusuke OtakeMakoto ItoTsuyoshi KobayashiGuanghao SunYukiya HakozakiTakemi Matsui
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2021 Volume Annual59 Issue Abstract Pages 312

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Abstract

Early detection of COVID-19-derived and other pneumonia is crucial to avoid disease spreading. Hence, we developed real-time pneumonia monitoring system and applied in clinical setting. System measures respiratory rates (RR) and heart rates (HR) and HF of heart rate variability which stands for parasympathetic nervous activity using microwave radars located beneath bed mattress. Nurse monitor displays, RR, HR, cardiopulmonary arrest, suspect of pneumonia, and suspect of arterial fibrillation responsible for brain infarction in real-time. In order to compensate drastic individual differences of vital signs in elderly patients, we adopted Mahalanobis's squared distance, a non-Euclidian distance determined by RR, HR and HF of the past 10 hours divided into anterior (before pneumonia pathogenesis) and posterior 5-hour periods (after pneumonia pathogenesis). Two out of 20 inpatients (8 males and 12 females, 74 +/- 14 years at Genki-kai Yokohama Hospital) developed pneumonia during 5-days validation, with sensitivity of 100% and NPV of 100%.

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© 2021 Japanese Society for Medical and Biological Engineering
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