2021 Volume Annual59 Issue Proc Pages 629-631
Magnetoencephalography (MEG) is an essential tool for non-invasive focus localization of epilepsy patients. However, little is known about the clinical value of MEG sharp transients (STs) when epileptic spikes are not found. At our hospital, 53 patients underwent comprehensive presurgical evaluations including head MRI, video EEG monitoring and MEG within the last 5 years. 15 out of 53 patients had only MEG STs. ECDs of STs were clustered in 6 patients. In 3 of them, clusters overlapped with structural lesions. Some dipoles overlapped with structural lesion in 1 patient without ECD cluster. 4 patients with clustered ECD and 5 patients without ECD cluster underwent surgical resection of structural lesions and all became seizure free. MEG sharp transients are less specific and difficult to localize compared with spikes, but good prognosis can be achieved by integrating with specific findings from other modalities.
