抄録
The opposition of the arterial vessel to the flow of cardiac output was simulated by the most minimized three component model consisting of two resistors and a capacitor. Thus, using the cardiac flow wave calculator, designed on the theoretical basis of the three component models, a trial was performed to calculate the flow wave of cardiac output from cardiac pulses such as blood pressure. The calculator has two adjusting mechanisms : time constant of a low pass filter and a potentiometer. The former is selected so that the wave matching the actual flow wave may be calculated, while the latter is adjusted so as to put the diastolic flow signal to zero level. Close agreement existed between cardiac flow waves observed and calculated by this calculator from blood pressure under the conditions induced by infusion with noradrenaline, isoproterenol and acetylcholine. Furthermore, each component of the three component models was computed from the calculated flow wave and the pressure wave under the same conditions described above.
