A new method for the prediction of the post-operative face shape in craniofacial surgeries was developed by using image processing and computer graphics. The post-operative face shape can be viewed in arbitrary three-dimensional (3D) directions, since it is predicted in a 3D world based on a convensional 2D schemes on a regular X-ray film. We have applied the proposed method to an actual patient after simulating a craniofacial surgery to the lower jawbone. The result showed that the predicted configuration of skin surface was well simulated.