抄録
Since the feature of evoked potential for each stimulus may vary from stimulus to stimulus according to physical or psychological conditions of the subject, the single sweep recording method has been investigated by many researchers. In our previous work, we observed variability of the peak latency among the single sweep P300 waveforms obtained by using band-pass filter, and proposed a method to estimate the physiological variability caused by the physiological factor, by subtracting the noise variability caused by the noise of back-ground EEG from the measured variability. In this paper, we generalized the estimation method of the physiological variability for the data obtained by using the morphological filter. In order to evaluate the method, we estimated the physiological variability of the peak latency of P300 in simulation data, and obtained the accurate estimation values, which did not depend on the adopted filter (morphological filter, band-pass filter). Furthermore, the method was applied to actual ERP data of 5 healthy adults, and the satisfactory results were obtained.