Transactions of Japanese Society for Medical and Biological Engineering
Online ISSN : 1881-4379
Print ISSN : 1347-443X
ISSN-L : 1347-443X
Blood Glucose Regulation Using Chaotic Model Prediction Including a Mathematical Model for Glucose Metabolism
Toshiro KATAYAMATetsuo SATOMikio SUGAKotaro MINATO
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2004 Volume 42 Issue 4 Pages 277-282

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Abstract
To date, there has been no standard method for predicting blood glucose in clinical use. In this paper, we discuss the development of a new controlling method that can improve the hyperglycemia state in Type II diabetes. Since the fasting blood glucose level is regulated by the balance of insulin secretion and resistance, a chaotic model is created by embedding the theorem of Takens from a stabilized time series of the fasting blood glucose level incorporating the mathematical model of the glucose-insulin metabolism. The fasting blood glucose level of the next morning can be predicted using a semi-fuzzy reconstruction method, and the optimal amount for the insulin injection before going to bed can also be calculated from the prediction. As a result, patients can regulate their lifestyle using this quantitative perspective. Under this regulation, both the chaotic model and the prediction become more stable and accurate over a long period of use.
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