The strains around the eye during the blink are measured for four human subjects to investigate the relationship between the wrinkle formation with aging and the strains by daily motion. In addition, the moisture content, the flexibility and the elasticity of the skin surface are measured for investigating the condition of the skin surface. For observing the wrinkle formed on the facial skin, the replicas of the skin surfaces are also collected. Results show that the relationship between the wrinkle and the strain distribution at the inner corner of the eye is different from that at the corner of the eye. The results indicate that different methods for the corner of the eye and the inner corner of the eye are required for avoiding the wrinkle formation.