Abstract
The vascular endothelial cell is the only interface between blood and tissue, where the metabolisc activity is very active. The large deformation of the vesicles is considered to be involved in these transport process. In this study, vesicular mechanics in cells is theoretically investigated. A system of nonlinear differential equations is derived according to the variational principle and is reduced to two point boundary value problem. The equations are solved through the Shooting method along with Newton-Raphson and Runge-Kutta method. The computed shape suggests that the effect of various parameters and outer cytoplasmic membrane are significant and these should be taken into account in numerical simulation.
