Bubble nucleation and growth processes in high-viscosity fluid during rapid decompression have an important role in volcanic eruption. In the present study, the rapid decompression experiments with one-phase fluid of silicone oil are conducted to investigate the influence of volatile substance on bubble nucleation. Bubble number density is measured from the observed images and compared with the previous study which has been experimented with two-phase fluid of silicone oil and acetone as volatile component. It is confirmed that volatile component have little effect on bubble nucleation in silicone oil.