Abstract
In the present study, Microbubbles are used as a contrast agent for ultrasound diagnosis. It is also expected to be use for the treatment. One of the possible applications is microbubble DDS. For that purpose, microbubbles need to be well-controlled for the generating process and manipulation. In this talk, Non-contact manipulation techniques of microbubbles are developed by controlling the ultrasound filed. A plane standing wave-type, a ring-type and the focused-type ultrasound are used to manipulate microbubbles. It is shown that Primary Bjarknes force is well-utilized to control the position of microbubble. Microbubble clusters are observed in the experiments and they show the complicated behaviors as bubble clusters. These behaviors are discussed through the comparison between the experimental observation and theoretical estimation.
