Currently, computational fluid dynamics (CFD) is a widely used analysis method in the medical field, and there are many studies investigating carotid lesions. However, outlet boundary conditions strongly affect CFD results. This is particularly remarkable in cases with high ICA stenosis rates. In those cases, there is still no appropriate outlet boundary condition. For this problem, new approaches of setting outlet boundary conditions are proposed for CFD simulations of the human common carotid arteries (CCAs) bifurcation based on the concept of energy loss minimization at flow bifurcation (Zhang et al. 2013). In this study, we investigate whether this approach is appropriate for CFD simulations in CCAs with high ICA stenosis ratios. The CFD results indicated that the tendency of outflow ratios is similar to that of empirical relationship.
