G020025 細胞ファイバーの機械織りによる生体組織の構築

尾上 弘晃; 五條 理保; 松永 行子; 桐谷 乃輔; 根岸-加藤 みどり; 栗林-繁富 香織; 下山 雄土; 竹内 昌治

doi:10.1299/jsmemecj.2012._G020025-1

セッションID: G020025

DOI https://doi.org/10.1299/jsmemecj.2012._G020025-1

会議情報

G020025 細胞ファイバーの機械織りによる生体組織の構築

尾上弘晃, 五條理保, 松永行子, 桐谷乃輔, 根岸-加藤みどり, 栗林-繁富香織, 下山雄土, 竹内昌治

著者情報

尾上弘晃
The University of Tokyo, Institute of Industnal Science : ERATO Biohybnd Innvation Project, Japan Science and Technology (JST)
五條理保
The University of Tokyo, Institute of Industnal Science : ERATO Biohybnd Innvation Project, Japan Science and Technology (JST)
松永行子
The University of Tokyo, Institute of Industnal Science
桐谷乃輔
The University of Tokyo, Institute of Industnal Science : ERATO Biohybnd Innvation Project, Japan Science and Technology (JST)
根岸-加藤みどり
The University of Tokyo, Institute of Industnal Science : ERATO Biohybnd Innvation Project, Japan Science and Technology (JST)
栗林-繁富香織
The University of Tokyo, Institute of Industnal Science : ERATO Biohybnd Innvation Project, Japan Science and Technology (JST)
下山雄土
The University of Tokyo, Institute of Industnal Science
竹内昌治
The University of Tokyo, Institute of Industnal Science : ERATO Biohybnd Innvation Project, Japan Science and Technology (JST)

会議録・要旨集フリー

詳細

抄録

This paper describes a fiber-shaped cellular building unit, named "cell fiber," for the construction of spatially-ordered 3D macroscopic tissues. The cell fiber, where the core of the fiber was cell-suspended extracellular matrix (ECM) hydrogel and the shell was Ca-alginate hydrogel, was continuously formed in a double co-axial laminar flow microfluidic device. Using the cell fibers, we demonstrate a fiber-based centimeter-scale 3D tissue constructs woven by our microfluidic weaving machine. We believe that our approach would be a powerful method for constructing macroscopic functional tissues with network-like spatially-ordered internal structures.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）