年次大会
Online ISSN : 2424-2667
ISSN-L : 2424-2667
セッションID: J053041
会議情報
J053041 陽イオンに覆われたHOPG基板上におけるDNA自己集合化に関する分子動力学解析
新居 良介竹内 博土井 謙太郎川野 聡恭
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DNA is expected to be utilized for technological applications due to its various characteristics. In our previous studies, self-assembled DNA networks on mica surface are investigated in detail by the use of atomic force microscopy. The mechanisms of self-assembly has also discussed on the basis of theoretical developments and computer simulations. In the present study, network formations of DNA can be observed on highly oriented pyrolytic graphite (HOPG) surface using electrophoresis of MgCl_2 solution as preprocessing, although DNA molecules have negative charges and usually does not adsorb on HOPG surfaces filled with jt electrons. In order to clarify the adsorption mechanism, we develop and perform MD computations using a coase-grained model. As a result, the network pattern formations, in which DNA fragments make bonds and bundle structures, are replicated by our simulations.
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© 2012 一般社団法人 日本機械学会
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