G0210203 Biocompatibility of Ti-based Bulk Metallic Glass Alloy

Abstract

Ti-based bulk metallic glasses are reported to have high strength, low Young's modulus and high corrosion resistance, indicating their potentials in biomedical applications. However a specific in vivo evaluation of its biocompatibilities has not been conducted yet. In this study, we implanted bars of Ti-based bulk metallic glass in rats' femoral bones and evaluated the tissue reaction and its component ions' diffusion in local area and whole body twelve weeks after the implantation. It showed that the Ti-based BMG (Ti40Zr10Cu34Pd14Sn2) alloy has a good biocompatibility and bone bonding ability that is equal to Ti implant, component ion diffusion was not detected in study period.