Premixed diesel combustion is one of the most promising technologies to simultaneously establish a higher thermal efficiency and lower exhaust gas emissions. In this paper, new-generation ceramic-combined prototype pistons were applied to evaluate the potential in a diesel engine with modern combustion systems. The experimental result shows that premixed diesel combustion in the engine with the ceramic-combined piston has almost comparable performance and exhaust emissions. With the ceramic combined piston, the cooling loss is reduced while the exhaust loss is increased, resulting in the unchanged indicated thermal efficiency.