水熱ホットプレス法を用いた多孔質β-TCP作製の試み

抄録

Recently, bone regeneration using a scaffold has been performed instead of autogenous bone grafting as a treatment for a bone defect portion caused by a disease such as osteosarcoma or an accident or the like. The scaffold material should have high strength. However, mechanical properties are poor due to the reduction in strength by porosity and brittleness of β-TCP. In order to solve the problem that the strength is low, we attempted to prepare samples using hydrothermal hot pressing method. - In this study, we prepared the samples by changing the conditions for preparing them, and measured the compressive strength and the porosity of samples. As a result, layer cracking occurred in the samples prepared under conditions of high pressure. Furthermore, cracks were generated after sintering the samples. Therefore, both the compressive strength and the porosity of the samples prepared under conditions of high pressure were lower. In order to reduce layer cracks, we prepared lower pressure to reduce layer cracking. Occurrence of layer cracking could be reduced by prepared at 20 MPa or less. The heating and the cooling rate during sintering was changed from 3 [°C/min] to 2[°C/min]. The temperature distribution of the sample was uniformed to suppress the occurrence of cracks. From the above results, we were succeed in preparing samples which have average compressive strength of 10.0 [MPa] and average porosity of 72.3 [%].